Smoller Lab at PNGU


Senior Data Analyst

The Psychiatric and Neurodevelopmental Genetics Unit under the Center for Genomic Medicine at Massachusetts General Hospital (MGH) is seeking a motivated, enthusiastic candidate to join our research group. Our research projects aim to leverage large-scale data resources including electronic health records, genomics, neuroimaging, and behavioral data across the spectrum of neuropsychiatric disorders and related phenotypes. The data analyst will be responsible for conducting data management and statistical analysis tasks for several large-scale studies.
Principal duties and responsibilities
  • Work with team to design and execute research plans to ensure that critical project requirements, timelines, and deliverables are met.
  • Database management and administration of large-scale, diverse datasets
  • Implement quality control, data security procedures and data audits for assurance of all research data
  • Perform complex data acquisition, storage, cleaning, and pre-processing
  • Performs advanced quantitative statistical analysis methods
  • Dissemination of results via conferences and journal publication
  • Acts as a statistical subject matter expert and resource for numerous projects
Skills / Abilities / Competencies Required
  • Extensive data science experience, including experience with statistical and machine learning approaches
  • Advanced knowledge of statistical analysis approaches (e.g., linear and logistic regression; longitudinal analyses)
  • Knowledge of bioinformatics data analysis pipelines to implement research projects
  • Must be able to work independently as well as part of a team in a fast-paced, highly collaborative and supportive environment
  • Ability to adapt to shifting priorities in response to changing deadlines and the needs of the lab
  • Excellent written and verbal communication skills
  • Excellent organizational skills
  • Excellent quantitative and organizational skills
  • Proven ability to work well in collaborative environment
  • Ability to perform complex statistics or biostatistics, data mining, database management, and computer programming (e.g., SAS, R, Unix).
  • Ability to perform genetic analysis
MA degree required in related field
2-5 years of experience in managing complex data required.

Post-doctoral Research Fellow

The Psychiatric and Neurodevelopmental Genetics Unit and the Precision Medicine Research Unit in the Massachusetts General Hospital (MGH) Center for Genomic Medicine has an immediate opening for a postdoctoral fellow position encompassing big data analytics, precision medicine, and psychiatric genomics. Our program is conducting studies aimed at the development and clinical translation of novel approaches to risk prediction and genomic medicine using high-dimensional data to advance precision psychiatry. Our research leverages large-scale data resources including electronic health records, genomics, neuroimaging, and behavioral data across the spectrum of neuropsychiatric disorders (e.g. autism, ADHD, psychotic, mood and anxiety disorders, PTSD) and related phenotypes (e.g. suicide, treatment response, brain imaging). Our highly collaborative and dynamic research environment includes leading scientists, clinicians, and trainees at MGH, the Broad institute, Partners Healthcare, Harvard Medical School, and the Harvard T.H. Chan School of Public Health.

Mentorship, training, and career development opportunities span precision and genomic medicine, neuropsychiatric genetics, and population health. We seek a highly motivated and dedicated MD or PhD with strong training in biomedical informatics, biostatistics, predictive analytics, machine learning/AI, computer science, applied mathematics, and/or statistical genetics with outstanding quantitative skills, proven ability to work well in a collaborative environment, fluency with all modes of communication in English, and strong writing skills.

To apply, please send a single email containing your CV and a short statement describing your qualifications for this position to

Partners Training Program in Precision Medicine

We are pleased to announce the call for applications for the Partners Healthcare Training Program (T32)  in Precision & Genomic Medicine. The training program is co-led by Jordan W. Smoller, MD, ScD and Heidi Rehm, PhD and supported by the National Human Genome Research Institute (NHGRI).  Our faculty comprise a broad range of leading scientists affiliated with the Partners Healthcare System (including Massachusetts General Hospital and Brigham and Women’s Hospital), Partners Personalized Medicine, Boston Children’s Hospital, the Broad Institute of MIT and Harvard, Harvard Medical School, and the Harvard T.H. Chan School of Public Health.

We seek talented applicants with a commitment to training in the diverse domains of precision and genomic medicine, including medical genetics and genomics, data science, molecular medicine, and implementation science. We are accepting applications for postdoctoral fellows to begin July 1, 2020

The training program brings together three outstanding components for a world-class training program in precision and genomic medicine: 1) an internationally-recognized faculty with expertise in precision and genomic medicine across a broad range of disciplines, 2) outstanding institutional resources bridging clinical, genomic, and data sciences, and 3) deep engagement with cutting edge, collaborative initiatives at the regional, national, and international levels to provide rich training experiences.

Funding is for 2-years and awards cover salary, travel to professional meetings, and other training-related expenses.

Any questions about the T32 program or eligibility can be directed to the Program Manager, Carol Whooley

All application materials are due Friday, March 6, 2020 by 5pm ET USA

Notification of awards will be made by April 1, 2020

Citizenship and Minority Recruitment

Per NIH guidelines, applicants must be a citizen or non-citizen national of the United States or have been lawfully admitted for permanent residence at the time of appointment. Underrepresented minority groups including, but not limited to, African Americans, Hispanic Americans, Native Americans, Alaskan Natives and Pacific Islanders are strongly encouraged to apply.

We look forward to reviewing your application.


Massachusetts General Hospital
Simches Research Building
185 Cambridge Street
Boston, MA 02114