Individuals at high risk for schizophrenia may benefit from early intervention, but few validated risk predictors are available. Genetic profiling is one approach to risk stratification that has been extensively validated in research cohorts.
With information provided by volunteers across the United States, All of Us is developing a robust data platform to support a wide range of health studies.
Researchers have identified specific genes that may trigger the development of sleep problems, and have also demonstrated a genetic link between insomnia and psychiatric disorders such as depression, or physical conditions such as type 2 diabetes.
This summer, I got an email with the subject line, “Help researchers at Mass. General or the Brigham make discoveries.” Think the Boston hospitals — Massachusetts General Hospital and Brigham and Women's Hospital — were hitting me up for a check? Wrong.
Mental illness affects one in six U.S. adults, but scientists' sense of the underlying biology of most psychiatric disorders remains nebulous. That's frustrating for physicians treating the diseases, who must also make diagnoses based on symptoms that may only appear sporadically. No laboratory blood test or brain scan can yet distinguish whether someone has depression or bipolar disorder, for example.
Attention deficit hyperactivity disorder, major depression, bipolar disorder and schizophrenia may be linked by common genetic risk factors, according to a new study published in The Lancet. Audie Cornish speaks with study author Jordan Smoller of Harvard Medical School.
For the first time, researchers have identified two genetic variants that predispose humans to major depressive disorder, according to a study published in Nature today. The finding is specific to Han Chinese women, so this isn't a universally relevant piece of information. Still, this discovery could help researchers get a handle on the biology of depression — in addition to enabling the identification of new drug targets.
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