Dr. Jordan Smoller is the MGH Trustees Endowed Chair in Psychiatric Neuroscience, Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health in Boston. He is Associate Chief for Research in the Massachusetts General Hospital (MGH) Department of Psychiatry and Director of both the Psychiatric and Neurodevelopmental Genetics Unit and the Precision Medicine Research Unit in the MGH Center for Genomic Medicine. Dr. Smoller is a Tepper Family MGH Research Scholar and also serves as Director of the Omics Unit of the MGH Division of Clinical Research and co-Director of the Partners HealthCare Biobank at MGH. He is an Associate Member of the Broad Institute and a Senior Scientist at the Broad’s Stanley Center for Psychiatric Research. He is also Vice President of the International Society of Psychiatric Genetics.
The focus of Dr. Smoller’s research interests has been:
He co-chairs the Cross-Disorder Workgroup of the international Psychiatric Genomics Consortium which has been examining how genetic influences transcend diagnostic boundaries. He is a PI in the Electronic Medical Records and Genomics (eMERGE) network and lead PI of the New England Precision Medicine Consortium as part of the NIH Precision Medicine Initiative’s All of Us Research Program. He is an author of more than 300 scientific publications and is also the author of The Other Side of Normal (HarperCollins/William Morrow, 2012).
Kate Bentley, PhD is a clinical psychologist whose research focuses on the prediction and prevention of suicidal and nonsuicidal self-injurious thoughts and behaviors. Dr. Bentley received her doctorate in clinical psychology from Boston University and completed her clinical internship at MGH in the cognitive-behavioral therapy track. She is currently funded by a five-year NIMH career development award, mentored by Dr. Matthew Nock at Harvard University and Drs. Jordan Smoller and Maurizio Fava in the MGH Department of Psychiatry.
Tian Ge, PhD is an applied mathematician and biostatistician who works at the intersection of neuroimaging science, genetics and statistics. His current research focuses on developing statistical and computational methods to integrate large-scale imaging, genomic, and biomedical data. Dr. Ge received his BS in Mathematics and PhD in Applied Mathematics from Fudan University, and a PhD in Computer Science from University of Warwick. He completed his postdoctoral training with Drs. Mert Sabuncu and Jordan Smoller at Massachusetts General Hospital and Harvard Medical School. He is currently an Instructor at Harvard Medical school, a junior faculty member in the Psychiatric & Neurodevelopmental Genetics Unit (PNGU), Center for Genomic Medicine, and is also affiliated with Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital. More information can be found on his personal webpage: https://scholar.harvard.edu/tge
Karmel Choi, PhD, is a postdoctoral fellow with Jordan Smoller, MD, ScD, and Karestan Koenen, PhD, through the T32 Training Fellowship in Psychiatric Genetics at the Harvard T.H. Chan School of Public Health. Her research focuses on the interplay of genetic and environmental factors that influence trauma and resilience across the life course. Her clinical work focuses on treatment of mood and anxiety disorders and stress-related health conditions, particularly in women. Karmel completed her PhD in Clinical Psychology at Duke University and her predoctoral clinical internship in Behavioral Medicine at MGH.
Heather Lee, PhD, is a postdoctoral research fellow at PNGU, working with Dr. Jordan Smoller. She recently completed her PhD in psychiatric epidemiology from Brown University, focusing on prenatal immune activation as a potential predictor of offspring’s cognitive and psychiatric outcomes in the New England Family Study. During her postdoctoral training at PNGU, she’s excited to investigate the etiologic connections between immunological and psychiatric disorders using electronic health records and GWAS data.
Yi-han Sheu, MD, ScD, is a postdoctoral research fellow working with Dr. Smoller. He received his MD degree at National Taiwan University, MPH in Healthcare Management and Policy, and ScD in Epidemiology, both at Harvard University. His doctoral thesis involves using electronic health records data to improve treatment decision in psychiatric disorders by combining machine learning, artificial intelligence, and epidemiological methods. His current interest is in improving healthcare quality by further extending the application of the methodologies above, as well as making progress in more general aspects of artificial intelligence, such as improved transfer learning and multi-modal knowledge representations.
Kristin Joyce is the assistant to Dr. Jordan Smoller. Kristin has held this position for over five years and has become an integral part of the PNGU team.
Emily Madsen graduated from SUNY Stony Brook University with a BS in biology specializing in developmental genetics. She previously worked closely with the clinical interpretation team of a clinical genetics laboratory focused on rare pediatric disorders. She is excited to learn more about complex trait genetics and psychiatric disorders.
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